The Barrier Problem
Your skin’s outer layer exists specifically to keep things out, and it is good at its job. That is why every exosome program here is delivered to depth rather than applied on top.
Now accepting a limited number of new patients each quarter · River Oaks, Houston
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Aesthetics
Skin Health
Skin quality is madebeneath the surface.
The skin program at Valere in River Oaks, Houston pairs microneedling with an exosome preparation, planned around your assessment and delivered to the depth where collagen is made, for skin that looks firmer, smoother and more radiant.
What It Is
Not a material that covers.A signal between cells.
Skin quality is produced in the dermis, the layer beneath the surface, where fibroblasts make collagen and elastin. Most skin products stay on the surface. This program is designed to reach the layer where the work is done.
The skin program uses exosomes: vesicles that mesenchymal stromal cells release, carrying proteins and genetic material between cells. They do not add material to your face. Delivered to the layer where skin is actually made, that signaling is designed to support the cells that build collagen and elastin, for skin that looks firmer, smoother and more radiant over time.
Microneedling is how they get there: a precise delivery route that carries each preparation to depth. Published research on umbilical cord derived secretome in skin and hair is available at PubMed Central.
Plain Definitions
Exosome
A nanoscale vesicle released by cells, carrying proteins, lipids, and RNA. It is a message rather than a material, passed from one cell to another.
Dermis
The layer beneath the visible surface where fibroblasts produce collagen and elastin. This is where firmer, smoother skin is built.
Fibroblast
The cell that builds and maintains the dermal matrix. It becomes less active with age, which is why it is the focus of this program.
Microneedling
Controlled microchannels that carry a preparation past the barrier layer. They carry exosomes to the dermis, where they are designed to work.
How It Works
Why deliverydepth matters.
Microneedling as the Route
Controlled microchannels open a path to the dermal layer. The needling and the exosome preparation are not two procedures stacked together. One is how the other arrives.
What Research Is Exploring
Published research explores how exosomes interact with fibroblasts and follicular cells, including collagen signaling and inflammatory signaling. It is the science our skin and scalp programs are built around.
How Results Build
Collagen is built, not applied. Fibroblasts synthesize it over weeks, and the remodeling that follows continues for months, so your skin keeps changing long after each session.
Results build over the following months as your body responds. Your care team maps your timeline at your assessment, so you know what to look for and when.
Built Around You
Every program startswith the right questions.
Skin that has changed quickly may be reflecting hormonal or metabolic shifts underneath. Addressing what is happening underneath helps your results last.
That is why an assessment comes before a protocol here, and why hormonal health is part of an aesthetic program rather than a separate conversation you would have to think to ask for.
Before-and-afters will be added here as Valerian results come in, shared with consent and labeled with the treatment, settings, and timepoint. Until then, your assessment is your personal preview.
How It Applies at Valere
Skin shows what is happening inside.We work on both.
Inside, Then Outside
Hormonal shifts, inflammation, nutrition, stress, and sleep all show up in your skin, often first. They are part of the conversation from your first visit, and a program that ignores them is only working on the surface.
Sourcing You Can Verify
The same standard as every cellular product here: strict AATB guidelines, FDA-registered labs, and batch-verified documentation on every vial. FDA registration is a facility standard, not a product approval. It is a standard few clinics disclose.
Decided by a Physician
Candidacy, protocol design, and depth settings are physician decisions here. Every plan is designed around your goals, so what you receive is built for you.
Clear Expectations, Set Early
What your program is designed to do, on what timeline, and how results build, all mapped out before you begin, so you can commit with confidence.
How It Works With the Rest
One program.Sequenced around you.
A skin program is never a stand-alone procedure. It sits inside one personalized protocol, and your assessment decides what runs alongside it, and in what order.
Skin & hair
Aesthetics
Exosome skin and hair programs delivered through microneedling.
Explore Aesthetics
Hormones
HRT & TRT
Testosterone for men, bioidentical hormones for women, with thyroid and cortisol markers reviewed alongside.
Explore HRT & TRT
Recovery
Peptides
Short chains of amino acids, many of the body’s own signaling molecules, dosed inside your protocol.
Explore Peptides
Scalp
Hair & Scalp
The scalp program: microneedling with an exosome preparation, for hair that looks fuller and healthier.
Explore Hair & ScalpNutrition, exercise, coaching, hormone optimization, peptide support, and supplement support are assessed alongside every program here.
See how a program is builtBecause your skin’s barrier layer exists to keep things out and is effective at it. An exosome applied topically does not meaningfully reach the dermal layer where fibroblasts and follicular cells actually are. Microneedling creates the channels that carry the preparation to depth. It is not an add-on to the exosomes. It is how they arrive. That is the difference between a product that sits on the surface and a program that works at depth.
Results build over the following months as your body responds. Collagen is synthesized over weeks and remodeled over months, so skin keeps improving well after each session, and hair, which grows in cycles, follows its own rhythm. Your care team maps your personal timeline at your assessment, so you know what to look for and when.
It is one of the most active areas in regenerative aesthetics. Published research examines mesenchymal stem cell derived secretome and exosomes in relation to fibroblast activity, collagen signaling, inflammatory signaling, and hair, including work specific to umbilical cord derived sources, available at PubMed Central. Your care team will walk you through that research at your assessment and show you how it informs your plan.
The procedure may look similar. What differs is what precedes it and what is in the vial. Here, a full assessment comes first, because hormonal health, inflammation, and lifestyle often explain skin and hair changes better than the mirror does. The exosome preparations follow strict AATB guidelines and come from FDA-registered labs, with batch-verified documentation on every vial, a standard few clinics disclose. And every plan is designed by a physician around your goals, so what you receive is built for you.
Yes, as Valerian results come in. Each image is shared only with the patient’s consent and labeled with the treatment, settings, and timepoint, so you can see what produced the change. Every image shows what is possible, and your own assessment shows how it applies to you.
No. Aesthetic and regenerative programs are not covered by standard insurance, and Valere operates as a private-pay practice. Cost depends on the target area, the number of sessions your assessment supports, and what runs alongside it, which is why it is discussed after your assessment rather than quoted from a menu. Payment plans and membership options are available.
Exosome preparations described on this page are investigational and not FDA approved to diagnose, treat, cure, or prevent any disease. They are supplied for individualized use as determined by the licensed physician, and candidacy is determined by physician evaluation. Individual results vary. This page is educational and does not constitute medical advice. Please consult your primary care provider.
Find the programbuilt for your skin.
Your assessment looks at your skin and the health behind it together, and builds one plan around both.
Private · By appointment only · River Oaks, Houston