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HRT & TRT

Normal range is where most people land.It is not where you function best.

Testosterone for men, bioidentical hormones for women, with thyroid and cortisol read in the same panel. The goal is not simply landing inside a reference range. It is finding the level where you feel like yourself again: clear, energized and strong.

What It Is

A reference range isa population average.

The number printed beside your result tells you where most people your age and sex fall. It does not tell you where you function best. Two people can sit at opposite ends of the same range and lead noticeably different lives: in energy, in recovery, in how clearly they think by mid-afternoon.

Hormone optimization at Valere in River Oaks, Houston means finding that individual level and building a protocol around reaching and holding it. For men that usually centers on testosterone. For women it centers on estradiol, progesterone, and often low-dose testosterone. For both it includes thyroid and cortisol, because those two govern how everything else behaves, and reading them fully completes the picture.

What this is: a protocol built by your care team around you, never a subscription or a standard starting dose. The panel comes first, your care team reads all of it, and your protocol follows from what it shows.

Read in Every Panel

Sex Hormones

Total and free testosterone, estradiol, progesterone, SHBG, LH, FSH, DHEA-S. Free matters as much as total, since SHBG determines how much is actually available.

Thyroid, Read Fully

TSH, free T3, free T4, and reverse T3. Reading all four shows the full picture of what your cells are actually receiving.

Cortisol

Cortisol shapes how every other hormone performs, so it is measured and accounted for in your protocol.

Safety Markers

Hematocrit, PSA where applicable, lipids, blood pressure, IGF-1, and metabolic markers, tracked at baseline and at every follow-up panel.

What It Is Used For

The biology is different.So are the programs.

Male hormonal decline is gradual and largely linear. Female hormonal change is neither. So each program is designed around its own biology.

For Men

Testosterone Replacement

Testosterone declines roughly one percent per year after thirty. Many men who feel the difference have been told they are “in range.” Here, TRT is initiated at the dose and delivery method your specific results warrant, with estradiol conversion, hematocrit, PSA, and blood pressure tracked at every follow-up, so you can get back to your energy, drive and strength.

Men’s Sexual WellnessLibido and function, assessed with hormonal statusMen’s Metabolic HealthVisceral fat, lean mass, insulin sensitivity

Hormone therapy is prescribed where clinically indicated following physician evaluation. Testosterone products carry a Limitation of Use for age-related hypogonadism. Individual results vary.

How It Works

Three variables shapeevery protocol.

Which hormones, by what route, and when it is started. Getting all three right is what makes a protocol work, which is why each is decided with you.

Which Hormones

Sex hormones, thyroid, and cortisol interact, so the panel reads all of them together and your protocol supports the whole system rather than a single number.

By What Route

Route and dose are matched to you. Published guidance notes that transdermal administration and lower doses may carry a different risk profile than oral for some outcomes, so your physician chooses the route with you.

And When

For women, timing relative to menopause onset shapes the benefit-risk picture. Your care team explains it clearly, so you can begin with confidence.

The Full Picture

The science hasmoved forward.

The safety picture for hormone therapy has changed meaningfully in recent years. Here is what the latest guidance says, so you can decide with confidence.

Testosterone & the Heart

What the 2025 label change means for you.

In February 2025 the FDA removed cardiovascular-risk language from the Boxed Warning across all testosterone products, following the TRAVERSE trial.

TRAVERSE enrolled 5,246 men aged 45 to 80 with hypogonadism and existing or high cardiovascular risk. Testosterone was noninferior to placebo for major adverse cardiac events.

Noninferior means not worse. It was designed to measure safety rather than to show a cardiac benefit.

A new warning about increased blood pressure was added at the same time. It applies across all testosterone products.

The FDA retained its Limitation of Use language for age-related hypogonadism. Treatment is based on a confirmed deficiency, not age alone.

Source: FDA class-wide labeling changes for testosterone products, February 2025.

Women & the Timing Question

Starting at the right time works in your favor.

Published position guidance holds that for women under sixty, or within ten years of menopause onset and without contraindications, the benefit-risk balance is favorable for vasomotor symptoms and for maintaining bone density.

Beyond ten years from onset, or past sixty, guidance describes the balance as less favorable as absolute risks rise, which is why timing is reviewed with you individually.

Risk varies by type, dose, duration, route, timing, and whether a progestogen is used. That is why every protocol is individualized.

Guidance is explicit that therapy should be individualized with shared decision-making and reassessed periodically, which is exactly how it is run here.

Source: The 2022 hormone therapy position statement of The North American Menopause Society.

Hormone therapy works best when it is prescribed by a team that reads the whole file, and every Valere protocol is built exactly that way.

How It Applies at Valere

Your care team is the constant.Not the algorithm.

Every Number, Reviewed With You

Not a portal summary and not a traffic-light chart. Your care team walks the full panel with you: what each marker means, where you sit, and what the data suggests.

Your Plan, Explained Up Front

Fertility planning for men who have not completed their family. Timing and route for women. Monitoring for everyone. All of it is covered before your protocol is written, so you start with complete clarity.

Monitored at Every Stage

Follow-up panels at six to eight weeks, then quarterly, with estradiol conversion, hematocrit, PSA where applicable, blood pressure, and lipids tracked at every stage. Follow-up is built into every program.

Inside a Program, Not Beside One

Nutrition, exercise, coaching, peptide support, and supplement support are assessed in the same program. Hormone therapy sets the conditions, and what you do inside those conditions shapes the result.

Common Questions

What Valerian patients askbefore they commit.

Hormone therapy is prescribed only where clinically indicated following physician evaluation. Testosterone products carry a Limitation of Use for age-related hypogonadism and a warning regarding increased blood pressure. All clinical decisions, including eligibility, rest solely with the licensed physician. Individual results vary. This page is educational and does not constitute medical advice. Please consult your primary care provider.

Your numbers will tell uswhat your symptoms cannot.

Your assessment begins with the full panel: sex hormones, thyroid, cortisol, and safety markers. Your care team reviews every one of them with you.

Private · By appointment only · River Oaks, Houston