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All Offerings Cellular Oxygenation & Recovery

EBOO.

Systemic reset at the cellular level.

Extracorporeal Blood Oxygenation and Ozonation. Your full circulating blood volume processed through a sterile closed-loop system — filtered, saturated with medical-grade ozone and oxygen, and returned. A physician-supervised therapy for Valerians who require a systemic reset that supplements and IV nutrients alone cannot reach.

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What It Is

Your blood, processed.
Your biology, reset.

EBOO — Extracorporeal Blood Oxygenation and Ozonation — is a physician-supervised therapy in which blood is continuously drawn through a sterile closed-loop system, filtered, saturated with medical-grade ozone and oxygen, and returned to the body. Unlike standard ozone IV therapies that treat a small volume of blood, EBOO processes the full circulating volume over the course of a single session. The clinical evidence on ozone therapy mechanisms is reviewed at PubMed (PMID 31861860).

The result is a systemic biological effect — not a localized one. Inflammatory byproducts and oxidative debris are filtered from the bloodstream. Oxygen delivery to tissues and cells is enhanced. Mitochondrial function — the cellular machinery behind energy production — is supported at a level that supplements and IV nutrients alone cannot reach.

At Valere, EBOO is offered as part of a physician-supervised program — not as a standalone session. Candidacy is evaluated at assessment. The number of sessions and the program it is integrated into are determined by your physician based on your clinical picture and biological goals. To understand how Valere structures programs from assessment through ongoing care, see How It Works.

What EBOO Supports

Cellular Energy Production

Ozone activates mitochondrial function and supports ATP production — the cellular energy currency that governs how you think, recover, and perform. When mitochondria are under-supplied, the fatigue that follows is systemic and persistent.

Systemic Inflammation Modulation

The filtration process removes inflammatory byproducts and oxidative debris from the bloodstream. Ozone simultaneously modulates inflammatory cytokine activity — addressing the biological environment that chronic inflammation creates, not just its downstream symptoms.

Oxygen Delivery

Enhanced oxygenation of the entire blood volume supports delivery to tissues, organs, and the brain — the organ most sensitive to oxygen availability. Cognitive clarity, reaction time, and sustained mental output are all downstream of this supply.

Immune System Balance

Medical ozone supports immune modulation — calming overactive immune responses while supporting pathogen defence. For Valerians managing chronic immune dysregulation or post-viral fatigue, this systemic reset is where other approaches fall short.

What to Expect

Unhurried. Private.
Clinically precise.

01

Physician Assessment

Your physician reviews your health history, current symptoms, and clinical goals. Contraindications — including certain blood disorders, coagulopathy, uncontrolled thyroid conditions, and severe cardiovascular instability — are confirmed before any session is recommended. Candidacy is always physician-determined.

02

The Session

Two IV lines are placed — one to draw blood, one to return it. The blood passes through a medical filtration system and is continuously saturated with medical-grade ozone and oxygen before being returned. Sessions run approximately 60–90 minutes. You remain seated and at rest throughout. No sedation. No downtime.

03

Program Structure

An initial course typically consists of 3–6 sessions depending on your goals and clinical presentation. Valerians focused on longevity maintenance may continue with monthly or quarterly sessions. The program is designed around your specific biological objectives — not a fixed package.

04

Timeline

Some Valerians notice improved energy and mental clarity within 24–48 hours of the first session. The cumulative effect of a full course — reduced systemic inflammation, improved oxygenation, restored mitochondrial function — develops over several weeks. Individual response varies and is discussed honestly at assessment.

"EBOO is an off-label clinical application of ozone therapy. It is not FDA-approved for the diagnosis, treatment, or prevention of disease. Outcomes are not guaranteed and vary by individual."

Your physician will provide an honest assessment of what this program can support for your specific biology and goals.

Why Valere

Most approaches address
one variable at a time.

The Valerians who come to EBOO have already tried the supplements, the IV drips, the dietary protocols. Something moved. Nothing resolved. EBOO operates at a systemic level those approaches don't reach — and at Valere, it is offered within a physician-supervised program, not as a walk-in service. It pairs particularly well with IV Therapy & Cellular Infusion and Hormonal Health & Vitality.

Physician-Supervised

EBOO at Valere is not a spa add-on. It is a physician-supervised clinical therapy with defined candidacy criteria, contraindication screening, and a program structure built around your specific goals. Your physician determines if you are a candidate and how the therapy integrates with your broader health program.

Systemic — Not Symptomatic

Standard ozone autohemotherapy treats 50–200ml of blood. EBOO processes the full circulating volume in a single session. The difference in scale is the difference between a localized effect and a systemic one — and it is why Valerians who have tried standard ozone therapies often report a meaningfully different response from EBOO.

Integrated Into Your Plan

EBOO does not exist in isolation at Valere. Where it compounds the effect of hormonal correction, regenerative biologics, or metabolic support — it is sequenced accordingly. Where it stands alone as the appropriate program — it is treated with the same clinical seriousness as every other offering.

Complete Discretion

A private suite. By appointment only. No waiting rooms. The environment reflects the standard of care — and the standard of discretion — that the Valerian who invests in this level of therapy expects.

Common Questions

What Valerians ask
before they commit.

Standard ozone autohemotherapy treats 50–200ml of blood per session — a meaningful but limited intervention. EBOO processes the full circulating blood volume continuously over 60–90 minutes. The biological effect is systemic rather than localized, which is why Valerians who have tried standard ozone therapy often describe the EBOO response as categorically different in scale and duration. The mechanism of action for ozone therapy is reviewed at PubMed (PMID 31861860).

The evidence base for EBOO specifically is still accumulating long-term clinical trial data, but its foundational mechanisms are well-supported. A 2020 review in the International Journal of Molecular Sciences concluded that ozone therapy activates immune, antioxidant, and pro-oxidant systems in ways that produce measurable biological effects. At the cellular level, EBOO's enhancement of mitochondrial oxygen utilization, reduction of inflammatory cytokines, and improvement in blood rheology are all supported by peer-reviewed research. What most Valerians notice clinically — improved energy, reduced brain fog, faster recovery — aligns with these mechanisms. Honest answer: the evidence is strong enough to use it clinically in appropriate candidates, and not yet sufficient for sweeping disease-treatment claims. Your physician will give you an honest picture of what the data supports for your specific goals.

When administered by trained medical professionals using medical-grade ozone and appropriate equipment, EBOO has a well-established safety profile. It has been used in integrative and regenerative medicine internationally for decades — a major safety review found adverse events in only 0.0007% of over 5.5 million treatments. That said, it is not appropriate for everyone. Specific contraindications — including G6PD deficiency, certain blood disorders, coagulopathy, uncontrolled hyperthyroidism, and severe cardiovascular instability — must be screened before any session. At Valere, that evaluation happens at assessment, before any recommendation is made.

Valere operates as a private-pay practice. EBOO is classified by insurance carriers as investigational or integrative medicine and is not covered by standard insurance plans. The cost reflects the medical-grade equipment, single-use sterile tubing and filtration circuits, physician oversight, and the clinical screening required before each session. Payment plans and membership options are available — contact us to discuss what works for your situation.

Yes — and in many cases it is most effective when sequenced alongside other programs. Valerians undergoing hormonal correction, regenerative biologics, or metabolic support often find that EBOO compounds the systemic benefit of those interventions by improving the cellular and inflammatory environment in which they work. It pairs particularly well with IV Therapy & Cellular Infusion and Hormonal Health & Vitality. Your physician will determine how EBOO integrates with your broader program at assessment.

Biological resilience isn't luck.
It's what Valerians build here.

Your assessment is where candidacy is confirmed and the program is designed. Private, unhurried, and physician-guided from the first appointment.

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Private  ·  By appointment only  ·  River Oaks, Houston